Calcium Sulfate as a Scaffold for Bone Tissue Engineering: A Descriptive Review

In regenerative approaches, scaffolds play a crucial role in defining the 3-D anatomical shape and microenvironment for cells, while maintaining space, favoring regeneration of new bone, preventing soft tissue migration bony lesion. A variety materials have been explored as bone regeneration. Metals are generally inappropriate such applications because they lack desired degradability biological environment requiring second surgery. Synthetic polymers can provide physical strength engineered chemical properties however, do not optimal ease handling or predictable biodegradation rate. contrast to these scaffolds, calcium sulfate, also known Plaster Paris, is highly biocompatible biodegradable material that one simplest synthetic bone-like grafts. It has sued graft orthopedics dentistry more than hundred years. The present review illustrates examines current advances regarding sulfate sources, various properties,scaffold forms, clinical engineering.Additionally,it describesNanocrystallinecalcium sulfate. Keywords: Calcium sulfate; Gypsum; Paris; Graft; Regeneration